Market Movers — June 10, 2026

The 100 most actively traded US stocks on June 10, 2026, ranked by volume — 29 up, 71 down. Here are the day's biggest moves and the headlines driving them.

The market take

GSK's acquisition of Nuvalent for oncology expansion drove the sole meaningful gainer today, with the cancer-focused biotech surging 39.3%. However, breadth tells the real story: a 71-to-29 down day reveals broad-based selling pressure that overwhelmed this M&A bright spot. Weakness spanned both high-conviction growth sectors and defensive plays, suggesting a shift in market appetite rather than sector-specific repricing.

The quantum computing cohort—IonQ, Rigetti, and D-Wave—all fell between 8.9% and 9.7% despite mixed news (IonQ opened a new R&D lab; D-Wave drew analyst bullishness). These moves look like profit-taking or valuation compression across the space rather than headline-driven selloffs. Uranium Energy's 15.5% drop on earnings-call coverage and Redwire's 15.2% decline following a "sharp one day drop" suggest some names are unwinding recent gains. The insider sale at Applied Optoelectronics (-17.2%) added credibility to selling pressure. DraftKings bucked the trend with an 11.3% gain as retail enthusiasm for its prediction platform remained intact, a rare bright spot in an otherwise heavy session.

Analyst commentary generated from the day's data and headlines — not investment advice.

Biggest moves today

• NUVL (Nuvalent, Inc.) ▲ +39.28% at $123.25 on 51.7M shares — GSK Buys Nuvalent To Deepen Oncology Focus And Future Lung Cancer Revenue (Simply Wall St.)
• AAOI (Applied Optoelectronics, Inc.) ▼ -17.17% at $162.88 on 26.7M shares — Applied Optoelectronics Insider Sold Shares Worth $2,050,700, According to a Recent SEC Filing (MT Newswires)
• UEC (Uranium Energy Corp.) ▼ -15.54% at $10.65 on 30.2M shares — Uranium Energy Corp (UEC) Q3 2026 Earnings Call Highlights: Strategic Advancements Amid ... (GuruFocus.com)
• RDW (Redwire Corporation) ▼ -15.19% at $15.75 on 68.6M shares — Assessing Redwire (RDW) Valuation After Sharp One Day Drop And Strong Multi Year Share Price Gains (Simply Wall St.)
• POET (POET Technologies Inc.) ▼ -12.30% at $10.77 on 43.2M shares — Why Poet Technologies Skyrocketed 72.6% Last Month But Is Sinking in June (Motley Fool)
• DKNG (DraftKings Inc.) ▲ +11.34% at $27.59 on 19.9M shares — DKNG Stock Eyes Best Month In A Year: Retail Can't Get Enough Of Predictions Platform Momentum (Stocktwits)
• IONQ (IonQ, Inc.) ▼ -9.73% at $56.69 on 35.1M shares — IonQ, Inc. (IONQ) Opens a New Quantum Computing R&D Lab in Boulder, Colorado (Insider Monkey)
• RGTI (Rigetti Computing, Inc.) ▼ -9.53% at $19.69 on 48.7M shares — Is Rigetti Computing, Inc. (RGTI) Among the Best Quantum Computing Stocks to Invest In According to Hedge Funds? (Insider Monkey)
• QBTS (D-Wave Quantum Inc.) ▼ -8.94% at $23.52 on 35.5M shares — B. Riley is Bullish on D-Wave Quantum Inc. (QBTS) (Insider Monkey)
• PLUG (Plug Power, Inc.) ▼ -8.78% at $2.91 on 69.3M shares — Corning, Enphase, and Plug Power Stocks Trade Down, What You Need To Know (StockStory)

Most active by volume

#	Ticker	Price	Change	Volume
1	NOK	$13.85	-5.07%	178.7M
2	NVDA	$208.19	-0.22%	179.6M
3	AAL	$14.09	+3.60%	149.7M
4	INTC	$107.92	-2.13%	145.7M
5	KEEL	$5.42	-4.24%	94.3M
6	MRVL	$266.88	-7.61%	92.2M
7	SOFI	$16.47	-0.18%	79.3M
8	MU	$935.89	-1.41%	72.5M
9	PLUG	$2.91	-8.78%	69.3M
10	RDW	$15.75	-15.19%	68.6M
11	ONDS	$9.65	-6.31%	68.3M
12	AUR	$6.16	-1.60%	59.9M
13	AAPL	$290.55	-3.64%	69.9M
14	CPNG	$15.91	+4.81%	58.2M
15	TSLA	$396.68	-3.00%	58.4M
16	ACHR	$5.32	-7.16%	53.6M
17	IREN	$54.02	-8.73%	56.5M
18	T	$22.71	+0.93%	52.5M
19	NUVL	$123.25	+39.28%	51.7M
20	GRAB	$3.30	-0.90%	51.3M
21	BB	$8.84	-4.84%	50.9M
22	PATH	$10.75	-3.76%	51.8M
23	RGTI	$19.69	-9.53%	48.7M
24	SMCI	$40.64	-7.62%	47.2M
25	MARA	$13.31	-3.41%	48.0M

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Market data from Yahoo Finance; insider data from SEC EDGAR Form 4. For research only — not investment advice. Verify on the official source before trading.